Generated by Rank Math SEO, this is an llms.txt file designed to help LLMs better understand and index this website. # Olive Net ## Sitemaps [XML Sitemap](https://olive-net.eu/sitemap_index.xml): Includes all crawlable and indexable pages. ## Pages - [Privacy Policy](https://olive-net.eu/privacy-policy/): This privacy statement was last updated on July 23, 2026 and applies to citizens and legal permanent residents of the European Economic Area and Switzerland. - [Cookie Policy](https://olive-net.eu/cookie-policy/): This Cookie Policy was last updated on July 23, 2026 and applies to citizens and legal permanent residents of the European Economic Area and Switzerland. - [Contact](https://olive-net.eu/contact/): Contact Drop us a line - [Publications](https://olive-net.eu/publications/): PUBLICATIONS - [Partners](https://olive-net.eu/partners/): ICOA has numerous collaborations and partnerships  with many research laboratories (CBM, I3MTO, LBLGC, INEM, GREMI, GICC, etc.), with CEA (ICOA is an academic correspondent laboratory LRC M09), with pharmaceutical companies (Servier through the joint laboratory) and through Competitiveness Clusters  (Polepharma and Cosmetic Valley) in region centre Val de Loire. Since 2012, ICOA is a member of two Laboratory of Excellence (LabEx), SYNORG and IRON. ICOA is also involved in numerous international relationships with industrial and academic partners. - [Impact](https://olive-net.eu/impact/): Olive-Net in research and innovation aims to stimulate development of technologically innovative solutions, based on environmentally friendly technologies for exploiting olive-based material and olive polyphenols. - [Workflow](https://olive-net.eu/workflow/): In the context of Olive-Net, a detailed and thorough workflow has been conceived and constructed based on the foreseen secondments and staff effort. Olive-Net work plan has been divided in seven complementary work packages (WP1-WP7) and relative tasks. The overview of the research plan could be summarized as follows: The collection and selection of raw materials (products and by-products) coming from olive tree and olive processing industry will be realized in task 1 of WP2 (T2.1). All samples will be extracted with techniques and methodologies aiming to their secondary metabolites content. In principal, environmentally friendly extraction techniques will be applied (PLE, MAE, UAE, SFE) (task 2 of WP2). Enrichment techniques will aim to the production of extracts with a high percentage in specific compounds (task 3 of WP2). Selected extracts will be analyzed in detail for their phytochemical content (WP3). In parallel, specific and selected constituents of the extracts will be isolated applying conventional techniques (task 4 of WP2). Also, semisynthetic derivatives of those molecules will be produced by bio- and chemical transformations (task 5 of WP2). The structure elucidation of pure compounds will be realized by obtaining data from HRMS and NMR spectrometry (task 2 of WP3). After the generation of the extracts they will be screened with a fast cell free antioxidant assay (task 1 of WP4). Based on these results extracts will be selected to proceed to cosmeceutical, nutraceutical and pharmaceutical applications and the corresponding assays will prove their properties. Specifically, anti-ageing and skin-whitening assays will be performed (task 2 of WP4). Also cell based assays will support the antioxidant and anti-inflammatory properties (task 3 of WP4). Results from WP2, WP3 and tasks 1, 3 of WP4 will be carefully co-evaluated for the selection of the most promising that will be further proceed to in vivo assays of animal models of inflammation-related disease. PK/PD studies will be performed and correlated to in vivo studies (task 5 of WP4). In silico tools will support the biological activities of the compounds and assess their toxicity (task 6 of WP4). Taken into consideration the results from the biological tests (WP4), specific extracts and compounds will be selected for pilot scale production and development of final products (WP5). Selected extracts and pure compounds destined for pharmaceutical, nutraceutical and cosmeceutical will be properly formulated to give a range of innovative products. WP6 embraces all the activities required for the successful dissemination of the results of the project to general public and scientific communities. WP7 includes all the procedures required for the successful management of the project. Finally but most importantly, WP1 includes all the requirements concerning the ethics of the projects. - [Objectives](https://olive-net.eu/objectives/): Olive-Net is joining an international and multidisciplinary consortium in order to exploit diverse raw materials coming from the olive tree for the development of active ingredients - [Project Description](https://olive-net.eu/project-description/): Olive-Net is an ambitious project based on state-of-the-art natural product chemistry and biology, in order to exploit raw materials coming from the olive tree for the development of novel active ingredients that could be used in the pharmaceutical, nutraceutical and cosmetic industry. - [Terms of Use](https://olive-net.eu/terms-of-use/): Before you start browsing through our website, please make sure that you have consulted and you accept the following terms governing the rights and obligations regarding the use of the website. Any use of the website https://olive-net.eu/ implies your express and unequivocal consent and agreement with these terms. In case of disagreement of the visitor with any of the terms, he / she must stop and avoid his / her browsing on the website, notifying the Company accordingly, if he / she so wishes. That is why we kindly ask the visitors of the website to carefully read the following terms of use. - [Olive Net](https://olive-net.eu/): OLIVE NET WELCOME TO OLIVE NET WELCOME TO OLIVE NET WELCOME TO About Us Description of the Project Olive-Net is an ambitious project based on state-of-the-art natural product chemistry and biology, in order to exploit diverse raw materials coming from the olive tree for the development of novel active ingredients that could be used in the pharmaceutical, nutraceutical and cosmetic industry. Read More